Mark Bishop

Analytical Chemistry and

Signal Acquisition/Analysis



Aryl Halides

Preparation

From Diazonium salts

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Halogenation

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Iodination with arylthallium compounds

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Reactions

Formation of Grignard reagents

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Substitution in the ring

X is a deactivating o,p director

Nucleophilic substitution of X, bimolecular displacement

Occurs only when:

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Nucleophilic substitution by elimination-addition

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ID may be exposed